Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generati

Introduction, The Basics of Oligonucleotide-Based Therapeutics, Hybridization-Based Drugs: Basic Properties 2_-O-Methoxyethyl Oligonucleotides, Hybridization-Based Drugs: Basic Properties Duplex RNA Drugs, Other Chemical Classes of Drugs, Therapeutic Applications, Index