This is the first textbook devoted entirely to understanding and treating necrotizing enterocolitis (NEC), one of the leading causes of death and disability in premature infants. NEC continues to occur in neonatal units across the world, and the overall mortality has remained stubbornly high since its first description decades ago. Despite significant research into NEC, and a greater understanding of its underlying causes, there is no single source of information to which the care team can turn for guidance. This book fills that important gap in clinical care.

In selecting the topics for this inaugural textbook, three guiding principles have been followed. First, to include chapters that provide detailed information for the medical team – the doctors and nurses, the therapists and pharmacists, the chaplains and the child life workers – so that each team member can optimally recognize, prevent and treat patients with this disease. Second, to ensure that chapters cover the depth and breadth of the latest clinical and scientific research into NEC, each selected to identify specific preventative strategies or therapies for this disease. Third, and perhaps most importantly, to focus not only on the child with NEC, but also on the child’s family, in order to provide comprehensive information about a disease that families have barely heard about, until the jarring day when their precious infant is affected by it.

This book therefore:

  • serves as a "how-to guide" for the care of the infant with NEC
  • summarises critical new research and offers guidelines for future key research areas
  • addresses the complex and difficult issues surrounding care of the critically ill infant suffering from NEC

Written for the entire health care team including paediatric surgeons, neonatologists, developmental paediatricians, epidemiologists, ethicists, child life professionals, therapists and specialist nurses, each team member will find this book of value. This book was written to demystify this cruel disease, and to unlock its closely held secrets of pathogenesis, diagnosis, treatment and prevention.

chapter 1|1 pages


Necrotizing Enterocolitis, The Stories of Its Tiny Patients, and the Journey Ahead

chapter 2|4 pages

Nursing Considerations in Necrotizing Enterocolitis

Management of Infant Stomas

chapter 3|2 pages

Nursing Considerations in Necrotizing Enterocolitis

Management of Central Venous Catheters

chapter 5|10 pages

Clinical Clues, Biochemical Indices, and Biomarkers

Diagnostic Considerations in Necrotizing Enterocolitis

chapter 6|11 pages

Imaging Considerations in NEC Diagnosis

Plain Films, Ultrasound, and Everything Else

chapter 8|4 pages

International Practice Patterns in NEC Management

North America, Europe, and Australasia

chapter 10|9 pages

Surgery for Necrotizing Enterocolitis

Indications, Techniques, and Outcomes

chapter 16|4 pages

Clinical Trials in NEC Research

Advances, Perils, and Pitfalls

chapter 18|4 pages

Necrotizing Enterocolitis in Unusual Cases

Term Infants, Congenital Anomalies, and Comorbidities

chapter 39|6 pages

The Silver Lining

The Small Intestinal Epithelial Barrier and Its Role in Necrotizing Enterocolitis