Fibrinolysis in Disease reviews the state of the art of basic and clinical aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books.
The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discusses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.

part Section I|42 pages

Molecular Biology of the Chief Regulators of the Fibrinolytic/Proteolytic Enzyme Systems

part Section II|225 pages

The Role of the Plasminogen Activation System in the Maintenance of Vascular Integrity

part B|189 pages

Fibrinolytic Abnormalities in Various Disease States

chapter Chapter 14|2 pages

Impaired Fibrinolysis in Cigarette Smokers

chapter Chapter 15|7 pages

Fibrinolysis and Inflammation

chapter Chapter 21|6 pages

Hypercoagulable State in Trauma Patients

chapter Chapter 25|8 pages

Fibrinolysis and Obesity

chapter Chapter 26|3 pages

PAI-1 Activity and Serum Lipid Levels

chapter Chapter 27|8 pages

Hyperfibrinolysis in Liver Cirrhosis

chapter Chapter 28|9 pages

Hyperfibrinolysis in Liver Transplantation